Food Ingredient Preservative Nisin Crystal Powder - Natural Preservative for Dairy and Meat
Introduction to Nisin Preservation Technology
Nisin represents the gold standard in natural food preservation, offering a powerful yet clean-label solution for controlling spoilage microorganisms. Our Nisin Crystal Powder is a highly concentrated, pure form of this bacteriocin peptide, specially processed to maintain maximum activity for food protection. As consumer demand for natural preservatives grows, nisin has emerged as the premier choice for manufacturers seeking to replace synthetic alternatives while ensuring product safety and extended shelf life.
Product Specifications & Key Characteristics
Source: Produced by fermentation of Lactococcus lactis
Purity: ≥95% nisin activity (2.5% minimum nisin content)
Form: Off-white to cream-colored crystalline powder
Solubility: Soluble in acidic aqueous solutions (pH
Stability: Maintains activity at boiling temperatures (121°C/15min at pH2)
Certifications: Complies with FAO/WHO JECFA, FCC, EU (E234) standards
Mechanism of Action & Microbial Spectrum
Nisin exerts its preservative effect through a unique dual-action mechanism:
Pore Formation: Binds to lipid II in bacterial cell membranes, creating pores
Cell Wall Inhibition: Interferes with peptidoglycan synthesis during cell division
Effective Against Gram-Positive Bacteria:
Listeria monocytogenes (including antibiotic-resistant strains)
Staphylococcus aureus
Clostridium botulinum spores
Bacillus cereus
Lactic acid bacteria (spoilage organisms)
Primary Food Applications
Dairy Products Preservation:
Cheese Processing: Extends shelf life by 50-100% in soft and hard cheeses
Yogurt & Cultured Dairy: Prevents post-fermentation spoilage
Condensed Milk: Critical for tropical climate distribution
Dairy Desserts: Maintains quality in high-moisture formulations
Typical Usage: 2.5-10ppm depending on product and risk factors
Meat & Poultry Protection:
Processed Meats: Controls Listeria in deli meats and hot dogs
Canned Meat Products: Prevents thermophilic spore outgrowth
Marinated Poultry: Extends refrigerated shelf life
Usage Level: 5-25ppm (often combined with nitrites or lactate)
Other Food Applications:
Canned Vegetables: Prevents flat-sour spoilage
Salad Dressings: Controls lactic acid bacteria
Beverages: Preserves acidic drinks and fruit juices
Bakery: Extends freshness of par-baked products
Technical Advantages for Food Manufacturers
1. Natural Preservation Benefits:
Clean-label alternative to chemical preservatives
GRAS status in multiple jurisdictions
No impact on product taste or aroma at recommended levels
2. Processing Stability:
Heat-resistant at acidic pH (survives pasteurization)
Stable during freezing and refrigeration
Maintains activity in high-salt environments
3. Synergistic Effects:
Enhances effectiveness of other preservatives
Allows reduction of nitrites in cured meats
Complements HPP and MAP technologies
Regulatory Status & Safety Profile
Global Approvals:
FDA: GRAS (21CFR184.1538)
EU: Approved as E234
China: GB 1886.231-2016
JECFA ADI: 0-33,000 IU/kg body weight
Safety Characteristics:
Non-toxic to humans (digested like dietary proteins)
No known allergenicity concerns
Over 50 years of safe commercial use
Naturally degraded by digestive enzymes
Quality Assurance & Production Standards
Our nisin production follows:
cGMP-compliant fermentation processes
Strict quality control at each production stage
Activity verification through bioassay
Complete traceability documentation
Typical Certificate of Analysis Includes:
Nisin potency (IU/mg)
Moisture content
Heavy metal limits
Microbiological purity
Residual solvent testing
Usage Guidelines & Best Practices
Optimal Application Parameters:
pH Range: Most effective below pH4.5 (stable at pH2-6)
Distribution: Requires uniform dispersion in product
Activation: Dissolve in 0.02N HCl or acidic media first
Combination: Often used with chelators (EDTA) for enhanced spectrum
Recommended Dosage Ranges:
Dairy products: 1-5ppm
Meat applications: 5-15ppm
Canned foods: 2.5-10ppm
Beverages: 0.5-2.5ppm
Why Choose Our Nisin Crystal Powder?
1. Product Superiority:
Higher purity than standard nisin preparations
Optimized crystal structure for stability
Consistent biological activity
2. Technical Support:
Application-specific dosage recommendations
Compatibility testing assistance
Regulatory documentation support
3. Supply Chain Advantages:
Temperature-controlled logistics
Flexible packaging options
Global regulatory compliance
Market-Specific Benefits
For Dairy Processors:
Natural solution for clean-label cheeses
Extends export product stability
Reduces spoilage losses
For Meat Producers:
Listeria control without synthetic additives
Allows nitrite reduction strategies
Meets natural/organic market demands
For Food Innovators:
Enables novel preservation systems
Supports "free-from" product development
Complements emerging technologies
Environmental Profile:
Biodegradable peptide structure
Non-persistent in environment
Sustainable fermentation production
Boiling point | 2967ºC |
density | 1.02 g/mL |
Fp | >110ð(230°F) |
storage temp. | -20°C |
form | solution |
Water Solubility | Soluble in water |
Merck | 13,6592 |



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About Beijing United Information Technology Co., Ltd.
Beijing United Information Technology Co., Ltd. (Stock Code: 603613. SH), founded in 2002 and listed on the Main Board in July 2019, is mainly engaged in industrial e-commerce and industrial Internet platforms. Based on industrial e-commerce and supported by industrial big data and industrial digitalization, the company provides online commodity trading, business information services and digital technology services of industrial products and raw materials for related industries. In terms of business model, it is called "the industrial version of Pinduoduo" and "the industrial version of JD.com".
About Beijing TDD E-commerce Co., Ltd.
Beijing TDD E-commerce Co., Ltd. (shortly named TDD Global) is the core subsidiary of Guolian Corporation (Stock Code: 603613.SH) and the first industrial Internetplatform of Duoduo Series Platforms. The company mainly engages in B28 e-commerce transaction serices of raw material and industrial products, digital supply chain serices, industrial digitalization serices and industrial big data serices, and is committed to promoting the deep integration of traditional industries and new technologies such as the Internet, Internet of Things, big data, intelligent manufacturing and block chain, etc.
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